Varshasnata Mohanty

DST-Women Scientist A

  • Basic and Allied Health Sciences
  • MSc (Area): Cancer cell and molecular biology
  • varshasnata.mohanty@gmail.com

 

Varshasnata Mohanty is a recipient of Women Scientist Scheme-A (WOS-A) from the Department of Science & Technology (DST), Government of India for the project titled “Identification of serum-based oral cancer biomarkers in tobacco chewers”. This study will help in the identification of candidate proteins that play a role in tumour aggressiveness, recurrence and poor survival rates in tobacco users compared to non-users and identify molecules which can serve as early detection biomarkers in oral cancer patients based on tobacco chewing habits. She obtained her M.Sc. degree in Cancer cell and Molecular Biology from the University of Leicester, United Kingdom.

Experience

  • Junior Research Fellow (Proteomics) at Yenepoya University, Mangalore, Karnataka
  • Junior Research Fellow (Jan 2015-July 2015) at SASTRA University, Tamil Nadu
  • Scientist Trainee-Cancer Biology (May 2014-Dec 2014) at LifeScience Intelligentsia, India
  • Quality Control Microbiologist (03/2013 – 01/2014) at Meadow Foods Ltd, United Kingdom
  • Quality Control Technician (07/2012 – 03/2013) at Meadow Foods Ltd, United Kingdom

Awards/Honors

  • DST-Women Scientist Award (DST WOS-A)
  • “Best performer of the year-2018” award by Yenepoya University, India for the year 2018
  • Lifetime membership of Proteomics Society of India (PSI)
  • GATE 2015 AIR 1290

 

 

Research interest/Area

Head and neck cancer, Oral cancer, proteomics, mass spectrometry, data analysis, biomarker discovery, clinical proteomics

Research

Head-and-neck cancer is the sixthmost prevalent cancer worldwide.Proteomic profiling of serum samplesfrom oral cancer patients with andwithout tobacco chewing habit will be carried outto identify signature molecules whichcan serve as early detectionbiomarkers. This will lead to theelucidation the key molecular eventsspecific to tobacco chewers and non- chewersand help improve patient outcomes.Further, key candidate molecules willbe validated in a larger cohort ofpatients.The successful outcome of the study will provide insights into the etiology of chewing-associated oral cancer

Publication

  1. Mohanty, V., Subbannayya, Y., Najar, M. A., Pinto, S. M., Kasaragod, S., Karuppiah, H., Sreeramulu, B., Singh, K. K., Dalal, S., Manikkoth, S., Arunachalam, C., Prasad, T. S. K. and Murthy, K. R. (2019). Proteomics and visual health research: Proteome of the human sclera using high-resolution mass spectrometry. OMICS: A Journal of Integrative Biology. In press.
  2. Yelamanchi, S. D., Tyagi, A., Mohanty, V., Dutta, P., Korbonits, M., Chavan, S., Advani, J., Madugundu, A. K., Dey, G., Datta, K. K., Rajyalakshmi, M., Sahasrabuddhe, N. A., Chaturvedi, A., Kumar, A., Das, A. A., Ghosh, D., Jogdand, G. M., Nair, H. H., Saini, K., Panchal, M., Sarvaiya, M. A., Mohanraj, S. S., Sengupta, N., Saxena, P, Subramani, P. A., Kumar, P., Akkali, R., Reshma S. V., Santhosh, R. S., Rastogi, S., Kumar, S., Ghosh, S. K., Irlapati, V. K., Srinivasan, A., Radotra, B. D., Mathur, P. P., Wong, G. W., Satishchandra, P., Chatterjee, A., Gowda, H., Bhansali, A., Pandey, A., Shankar, S. K., Anita Mahadevan, A. and Prasad, T. S. K. (2018). Proteomic analysis of the human anterior pituitary gland. OMICS: A Journal of Integrative Biology. 22, 759-769.
  3. Karthikkeyan, G., Subbannayya, Y., Najar, M. A., Mohanty, V., Pinto, S. M., Arunachalam, C., Prasad, T. S. K., and Murthy, K. R. (2018). Human optic nerve – an enhanced proteomic expression profile. OMICS: A Journal of Integrative Biology. 22, 642-652.
  4. Abdulla, R.*, Adyanthaya., S., Kini, P., Mohanty, V., D’Souza, N. and Subbannayya, Y.* (2018). Clinico-pathological analysis of oral squamous cell carcinoma among the younger age group in coastal Karnataka, India- A retrospective study. Journal of Oral and Maxillofacial Pathology.