Proteomics of In Vivo Models of Ischemic Stroke: A Systematic review with a Systems Biological Perspective

Certain proteins are detected in multiple brain locations with either identical or non-identical regulation among the respective locations. Green represents upregulation, and red represents downregulation. For example Anxa1, Fga, Ctss, C3 are upregulated in both cortex (2/24 h tMCAO) and hippocampus (1.5/24 h tMCAO). In contrast, Pp2A is downregulated in cortex while upregualted in basal ganglia following 24 h pMCAO.