Mohammed Altaf Najar

UGC-SRF

  • Phosphoproteomics (Mass-spectrometry Based)
  • MSc (Area): Biochemistry
  • altaf@yenepoya.edu.in

Mohd. Altaf Najar obtained his M.Sc. degree in Biochemistry from University of Kashmir, Jammu and Kashmir, India. He has worked on anti-inflammatory effect of Hypericumperforatum in mice as a part of M.Sc. dissertation at University of Kashmir. He is funded by a Junior Research Fellowship from University Grants commission, Government of India. At present, he is involved in high resolution mass spectrometry-based identification of kinase signaling networks in gastric cancer.

Awards/Honors

  1. Attended an International conference “7th Annual meet of the INDIAN ACADEMY OF BIOMEDICAL SCIENCES” conducted by the Department of Clinical Biochemistry, Sher-I-Kashmir Institute of Medical Sciences Srinagar, Kashmir from 20th – 22nd April, 2018 and secured “First place” in poster presentation.
  2. Attended 87th Annual meeting and Conference of Society of Biological Chemists (India), 2018 in Manipal academy of Higher Education, Manipal, from 25th to 27th of November 2018, securing Best Poster award.

 

 

Research interest/Area

Proteomics, Molecular biology, Cancer biology

Research

Gastric adenocarcinoma also known as gastric cancer affects the stomach, and is one of the leading causes of cancer related deaths. About 95% of gastric cancer belongs to the adenocarcinoma. Incidence of disease is increasing day by day because of its poor diagnosis at early stage. Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. CAMKK2 belongs to serine therione protein kinase pathway. The signaling mechanism perturbed by CAMKK2 in gastric cancer is still not fully understood. In the present study we wish to decipher the downstream signaling mechanism of CAMKK2 in the development of gastric cancer.

Publication

  1. Subba, S., Pinto, S. M., Kasaragod, S., Chatterjee, O., Najar, A. M. and Prasad, T. S. K. (2018). Nuclear proteome of an orphan legume – Cajanuscajan L. Journal of Proteins and Proteomics.
  2. Advani, J., Verma, R., Chatterjee, O., Rex, D. A. B., Najar, M. A., Ravishankara, N., Suresh, S., Pachori, P. K., Gupta, U. D., Pinto, S. M., Chauhan, D. S., Tripathy, S. P., Gowda, H. and Prasad, T. S. K. (2018). Rise of clinical microbial proteogenomics: A multi-omics approach to non-tuberculous mycobacterium – the case of Mycobacterium abscessus UC22. OMICS: A Journal of Integrative Biology.
  3. Karthikkeyan, G., Subbannayya, Y., Najar, M. A., Mohanty, V., Pinto, S. M., Arunachalam, C., Prasad, T. S. K., and Murthy, K. R. (2018). Human optic nerve – an enhanced proteomic expression profile. OMICS: A Journal of Integrative Biology.
  4. Varshasnata Mohanty , Mohammed Altaf Najar, Yashwanth Subbannayya, Sandeep Kasargod, Hilda Karuppiah , Sreeramulu Bhuvaragavan, Kunal K. Singh, Sunita Dalal, Shyamjith Manikkoth, Cynthia Arunachalam, Sneha M. Pinto, T. S. Keshava Prasad, Krishna R. Murthy (2018). Proteomic analysis of human sclera tissue using high resolution mass spectrometry. OMICS: A Journal of Integrative Biology.

 

 

 

  1. Yashodhar P. Bhandary, Sadiya Bi Shaikh, Mr. Mohd. Altaf Najar, Dr. Ashwini Prabhu, Dr. Prashant Kumar Modi and Dr. T. S. Keshava Prasad,“Molecular Biomarkers for Detection of Idiopathic Pulmonary Fibrosis”, Indian Patent, Provisional specification, 2019, 201941048222.