Sayali C. Deolankar

ICMR-SRF

  • MSc (Area): Applied Microbiology
  • sayali@yenepoya.edu.in

Sayali Deolankar is a Indian Council of Medical Sciences- Senior Research Fellow working at Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre. She obtained her M.Sc. in Applied Microbiology from VIT University, Vellore, India. As part of her masters dissertation she worked on a project entitled “Generation of fluorescent biosensor constructs for Src family of kinases”, at inStem-NCBS, Bangalore. Subsequently she worked as a Senior Research Fellow at the National Institute of Mental Health and Neuro Sciences (NIMHANS)- Bangalore for the project “Family based association study of glutaminergic genes with obsessive compulsive disorder in a South Indian population”. Currently she is involved in the proteomic analysis of neurodegenerative diseases at CSBMM.

Experience

  • ICMR Senior Research Fellow (Oct 2018 – till date) – Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemd to be University), Mangaluru, India
  • ICMR Senior Research Fellow -National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India
  • Senior Research Fellow (Aug 2017 – Sept 2018) – Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemd to be University), Mangaluru,  India
  • Lecturer (Jul 2014 – Dec 2014) – MGM- Institute of Biosciences and Technology, MGM Hospital Campus, Aurangabad, India

Awards/ Honors

  • Indian Council of Medical Sciences- Senior Research Fellowship Award
  • Best Poster Award: “Identification, Purification and Pharmaceutical Application of Enzymes from Bacillus sp. ” at 6th International Conference on Science, Engineering and Technology (SET), organized by VIT University, Vellore. (Apr. 2013).

 

Research Interest/Area

Proteomics, PTM-biology, molecular biology and neurodegenerative diseases

Research

Ms. Sayali’s study focuses on understanding molecular substrates of Alzheimer’s Disease (AD) by proteomics and discovery of novel post-translational modifications which may aid in development of novel diagnostics and improve management strategies. Alzheimer’s is a complex neurological disorder and a major public health burden in both developed and developing countries. Post-genomic technologies such as proteomics and intelligent mining of multi-omics data offer new prospects for diagnostics and therapeutics innovation for AD. Her Ph.D. research focus is on deciphering molecular mechanism of neuroprotection conferred by traditional medicine in the management of AD.

Publications

  • Datta, K. K., Patil, S., Patel, K., Babu, N., Raja, R., Nanjappa, V., Mangalaparthi, K. K., Dhaka, B., Rajagopalan, P., Deolankar, S. C., Kannan, R., Kumar, P., Prasad, T. S. K., Mathur, P. P., Kumari, A., Manoharan, M., Karunakaran, C., Murugan, S., Sidransky, D., Gupta, R., Gupta, R., Khanna-Gupta, A., Chatterjee, A., Gowda, H. (2019). Chronic exposure to chewing tobacco induces metabolic reprogramming and cancer stem cell-like properties in esophageal epithelial cells. Cells.
  • Deolankar, S. C., Patil, A. H., Koyangana, S. G., Subbannayya, Y., Prasad, T. S. K. and Modi, P. K. (2019). Dissecting Alzheimer’s disease molecular substrates by proteomics and discovery of novel post-translational modifications (PTMs). OMICS: A Journal of Integrative Biology.
  • Bhat, S. A., Gurtoo. S., Deolankar, S. C., Fazili, K. M., Advani, J., Shetty, R., Prasad, T. S. K., Andrabi, S., Subbannayya, Y. (2019). A network map of netrin receptor UNC5B-mediated signaling. Journal of Cell Communication and Signaling.
  • Taj M J RJ, Ganesh S, Shukla T, Deolankar SC., Nadella RK, Sen S, Purushottam M, Reddy YCJ, Jain S, Viswanath B (2018). BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response. Asian Journal of Psychiatry.
  • Deolankar S.C, C. Ishita, K.V. Bhaskar Rao (2015)Evaluation of plant growth promoting activity of rhizophere bacteria of different crop plants. Research Journal of Pharmaceutical, Biological and Chemical Sciences.
  • Deolankar S.C., K. Sahithya, L. karthik, Gaurav Kumar, K.V. Bhaskar Rao (2013). Isolation, Purification and Application of Enzymes from Bacillus sp. Research Journal of Pharmaceutical, Biological and Chemical Sciences.