YRC YRC
Telephone

+91-824-2204668

Email Address

yrcoffice@yenepoya.edu.in
yrc.services@yenepoya.edu.in

Office Address

University Road, Deralakatte,
Mangalore 575018

YRC YRC

The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission

  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

Divisions

Laboratory Services

Cancer Research and Therapeutics

Laboratory Services

Center for Systems Biology and Molecular Medicine

Laboratory Services

Division of Cell Biology and Molecular Genetics

Laboratory Services

Division of Data Analytics, Bioinformatics, and Structural Biology

Laboratory Services

Division of Microbiology and Biotechnology

Laboratory Services

Division of Neuroscience


Laboratory Services

Stem Cells and Regenerative Medicine Center

Laboratory Services

Smart Materials and Device

33

FACULTY

45

PhD Awarded

35

PATENTS

532

PUBLICATIONS

48

EXTRAMURAL GRANTS

News and Updates

MICON 2024 - Microbes for a Sustainable Future – A National Conference on 24th and 25th January 2024.

Workshop on Fundamentals and Techniques in Proteomics - Organized by CSBMM on May 29th & 31st May 2025.

Hands on Workshop on Metabolomic Analysis: Unlocking the Power of Mass Spectrometry - Organized by CSBMM on 26th & 28th May 2025.

Science Outreach Programme on 25th May 2025.

One Day Workshop on “Grant Writing for Early-Career Researchers: Breaking into Funding” - Organized by CSBMM on 23rd & 24th May 2025.

10th Annual State-level Conference of AMBKCCON 2025- Insight into Women’s Health - organized by CBMG division, in collaboration with the Biochemistry Department on 21st May 2025.

One Day Workshop on “Single Cell and Spatial Multiomics” - Organized by CSBMM on 12th March 2025.

International Women’s Day 2025 Celebration on 8th March 2025.

National Science Day celebration on 28th February 2025.

“Microglia and Neural Rhythms In Alzheimer's disease” – A Special Guest Lecture By Dr. Chinnakkaruppan Adaikkan on 20th February 2025.

The 4th National Conference MiCON 2025 on “Divergence and surveillance of microorganisms” on 25th January 2025.

Annual Day Celebration on 31st December 2024.

The snake Feeders: Ecology, Conservation and Snake Bite Solutions – A awarness session by Mr. Rithan Bopanna KG on 20 th November 2024.

Multi-omics and System Biology Approach Reveals Mitochondrial Associated Protiens In Alzheimer’s Diseases Progression – A Special Guest Lecture by Dr.Kaushik Kumar Dey on 16 th November 2024.

Mass spectrometry-based workshop on metabolomics and data analysis conducted from 26th to 28th September 2024.

Molecular Biology Techniques – A hands on training on 3rd to 6th September 2024.

Metabolomics – A workshop conducted from 3rd to 5th September 2024.

Cardiovascular Disease in India and the establishment of CSIR longitudinal cohort by Dr. Shanthanu Sengupta- A Guest Lecture on 4th September 2024.

Financial Planning: Get early, paving way to Vikasit Bharath- A guest talk by Ms. Sandhya .T. on 29th August 2024.

Basics of Data Analytics (Hybrid Mode) – A Workshop – 26th August to 6th September 2024.

Parkinson’s Disease: Our two lines to reconnoitre the Neurobiological Basis for Pathogenesis – A special Guest talk by Dr. Phalguni Anand Alladi on 24th August 2024.

Sadbhavana Diwas Celebration by NSS Unit – 20th August 2024

Aligning Grant Proposal with Sustainable Development Goals (SDG) for Viksit Bharat – A Symposium on 10th August 2024

Felicitation to Mr. Kushalappa Gowda for achieving a world record for a 25-hour yoga marathon on 2nd August 2024.

Computer - Aided Drug Design with BIOVIA Discovery Studio – Hands on Workshop – 1st to 2nd August 2024.

Understanding Office Ergonomics and Preventive Strategies in Musculosketal Disorders – A guest talk by Mr. Satyaraja. R. on 16th July 2024.

Navigating Intramural Funding Process and Application Requirements - A Workshop on 6th Jul 2024.

Biochemical and Biophysical Characterization of a Cancer drug target-Poly (ADP-ribose) polymerase 1 – A special guest lecture by Dr. Rajakumar Eerappa on 6th July 2024.

Mansoonia – Health Screening Camp and Awareness Program on 27th and June 28th 2024.

The Astrocyte Enigma: Unravelling the mystery of alpha synuclein pathology in Parkinson’s disease – A Special Guest Lecture by Dr. Aishwarya Raj on 20th June 2024.

Beating Burnout – A Guest Talk by Dr. Ravichandra Karkal on 19th June 2024

Global Warming – Awareness Program on 11th June 2024.

Enhancing Student Centred Teaching and Assessment – Short term Faculty Development Course on 27th to 29th April 2024.

Basic Biology and Clinical Application – Flow Cytometry workshop on 14th and 15th April 2024.

Drosophila Genetic Techniques – Hands on training on 28th to 30th March 2024.

National Science Day – 2024 celebration on 28th February 2024.

BUB1: A Multifaceted Kinase and its role in DNA Damage Signalling – A Special Lecture by Dr. Shyam Nyati on 19th February 2024.

Announcements

Call for PhD Admissions 2025-2026 Click

Achievements

Publications

  1. Narayanan S, Priyadarsanan DR, Ranjith AP, Sahanashree R, Neelavar Ananthram A. Rediscovery and phylogenetic position of a long-lost Typhloperipatus williamsoni Kemp, 1913 (Onychophora: Peripatidae) after 111 years from Arunachal Pradesh, India. Journal of Natural History. 2025;59(17-20):1167-80.
  2. Suchitha GP, Upadhyay SS, Pervaje R, Prasad TK, Dagamajalu S. Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach. BioImpacts: BI. 2025;15:30568.
  3. Farooq J, Sultana R, Prabhu A, Kayarohanam S, Gupta G, Subramaniyan V. Mitigation of 5-Fluorouracil-Induced Nephrotoxicity: The Protective Role of Thymoquinone and Hesperidin in vitro and in vivo. 2025.
  4. Gopalakrishnan AP, Shivamurthy PB, Ahmed M, Ummar S, Ramesh P, Thomas SD, Mahin A, Nisar M, Soman S, Subbannayya Y, Raju R. Positional distribution and conservation of major phosphorylated sites in the human kinome. Frontiers in Molecular Biosciences. 2025;12:1557835.
  5. Rai P S, Bhandary YP, YM S, B A, Bhandary R, RH P, KG N, CG S, Alva P, Katyayani P, Shetty S. Interlinking the Cross Talk on Branched Chain Amino Acids, Water Soluble Vitamins and Adipokines in the Type 2 Diabetes Mellitus Etiology. Endocrine, Metabolic & Immune Disorders-Drug Targets. 2025;10:757-766.
  6. Narayanan V A, Yamajala RB, Venkatesan J, Pang MG, Gedda G. Emerging Carbon Dots Nanomaterials for Ovarian Cancer Diagnosis and Therapy. Current drug targets. 2025;1:1-16.
  7. Manzoor M, Suryavanshi MV, Mujeeburahiman M, Arun AB, Miller AW, Shouche YS, Rekha PD. Urine microbiome profiles in patients with different types of kidney stones. FEMS Microbiology Letters. 2025;372:fnaf054.
  8. Aravind A, Shaji V, Ahmed M, Dagamajalu S, Vijayakumar M, Prasad TS, Raju R. An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions. Frontiers in Immunology. 2025;16:1608101.
  9. Shaji V, Rafi A, Ahmed M, Gopalakrishnan AP, Soman S, Revikumar A, Prasad G, Jayanandan A, Raju R. Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2. Frontiers in Cellular and Infection Microbiology. 2025;15:1554760.
  10. Prabhu VD, Hegde S, Prabhu A, Abdulla R, Prabhu RV, Bhandary Y. Allium Sativum as a Novel Therapeutic Agent in the Treatment of Oral Squamous Cell Carcinoma: An In-Vitro Cell Line Study. Journal of Orofacial Sciences. 2025;17(1):70-4.
  11. Panakaje N, Parvin SR, UM B, Nashifa F, Sheikh N, Irfana S, Nihal M, Aneesh A AK. Islamic principles for Jamaat collaboration and sustainable business: how organizational learning and financial capacity shape environmental outcomes. Journal of Islamic Accounting and Business Research. 2025.
  12. Sequeira JP, Upadya VH, Rekha PD. Correlation Between Inflammatory Mediator Levels and Clinical Symptoms in Temporomandibular Joint Disorders: Biochemical Analysis and Treatment Outcomes Following Arthrocentesis and Sodium Hyaluronate Injection. Journal of Maxillofacial and Oral Surgery. 2025:1-7.
  13. Parvin SR, Panakaje N, Madhura K, Irfana S, Kulal A. Stock market participation through socialization: exploring the intervening role of financial well-being. South Asian Journal of Business Studies. 2026;15(1):63-84.
  14. Priyadarshini S, Bhat RS, Bindu AG, Nagaraj P, Rekha PD. Electrodeposition of Anticorrosive and Antimicrobial Cu-Mn Coating on Mild Steel Using Single Bath Technique. Journal of Materials Engineering and Performance. 2025:1-4.
  15. Bharadwaj N, Nenavath J, Subramanian M, Upadhyay SS, Prasad TS, Hoti SL. Melanin Biosynthesis and Omics: Homogentisate Pathway Dysfunction Drives Pyomelanin Production in Mutant Bacillus thuringiensis var. israelensis MB-24. OMICS: A Journal of Integrative Biology. 2025;29(10):502-14.
  16. Velachery S, Mascarenhas R, Umar D, Prasad TS K, Shetty S. Tracking metabolic changes in the oral environment after multi-bracket treatment via salivary metabolomics. Clinical and Investigative Orthodontics. 2025:1-2.
  17. Baby BM, Subramaniyan Y, Rekha PD. Pantoea piersonii (basionym kalamiella piersonii) as an emerging pathogen: clinical manifestations, diagnostic challenges, and resistance threats. Folia Microbiologica. 2025:1-7.
  18. Bhagya N. Cascabela thevetia (L.) lippold.-a review on its phytochemistry, pharmacology and toxicity. Natural Product Research. 2025.
  19. Kadamthodi AM, Panwar A, Shrungeswara AH, Vijayakumar P, Prasad TS, Raut AA, Mishra A. Metabolomic profiling and identification of potential biomarkers of highly pathogenic avian influenza (H5N1) in chicken. Frontiers in Cellular and Infection Microbiology. 2025;15:1540290.
  20. Sequeira JJ, Krishna M S, van Driem G, Mustak MS, Das R. Novel 4400-year-old ancestral component in a tribe speaking a Dravidian language. European Journal of Human Genetics. 2025:1-1.
  21. Kaur R, Kudva AK, D’souza R, Baliga MS, Kaushal N. Fruitful Interventions: A Narrative Review Addressing the Emerging Role of Antioxidant Fruits in Combating IBD-Driven Colorectal Cancer. Mini-Reviews in Medicinal Chemistry. 2025.
  22. Mamatha BC, Mohd S, Harish V, Prabhu A, Bidye DP, Dixit SR, Revanasiddappa BC, Pai A, Shaik S. Riboflavin and Thymine from Abutilon indicum Linn. Mitigate Allergic Responses: An Integrated network pharmacology, In-silico analysis, MD Simulation, In vitro and Ex vivo Studies. Journal of Computational Biophysics and Chemistry. 2025:1-24.
  23. Li WJ, Gonzalez JM, Rekadwad BN. Investigating the role of microorganisms in ecosystems and their interactions with the humans, animals, plants, and environment interface. Frontiers in Microbiology. 2025;16:1710906.
  24. Sangamesh VC, Jayaswamy PK, Bhandary YP, Moideen FM, BH G, Shetty K J, Patil P, Narasimhamurthy RK, Kulkarni A, Shetty P. Antagonistic Regulation of Pro-Inflammatory AnnexinA2 and Anti-Inflammatory AnnexinA1 in the Pathogenesis of Idiopathic Pulmonary Fibrosis. Cell Biochemistry and Biophysics. 2025:1-4.
  25. Panakaje N, Zuha A, Parvin SR, Sheikh N, Shaid M, Irfana S, V M. Exploring the role of islamic ethical training and business integrity in shaping ethical decision-making and business performance: a mediated–moderated analysis. Journal of Islamic Accounting and Business Research. 2025:1-33.
  26. Ramesh P, Prasad TS. Future of clinical proteomics: could targeted multi-protein panels supplant low-throughput methods?. Expert Review of Proteomics. 2025;22(11-12):447-52.
  27. Shali Lasrado B, Panakaje N, Parvin SR, Kagzi M, Sheikh N, Irfana S, Banu W. Skills assessment and development scale for rural women entrepreneurs: conceptualization and validation. Journal of Small Business and Enterprise Development. 2025;32(7):1530-57.
  28. Shaji V, Anil A, Jabbar AA, Mahin A, Rafi A, Revikumar A, Soman S, Prasad G, Pinto SM, Subbannayya Y, Jayanandan A. Uncovering human kinase substrates in nipah proteome. Frontiers in Bioinformatics. 2025;5:1678189.
  29. George M, Dcunha L, John L, Mahin A, Sanjeev D, Gopalakrishnan AP, Nisar M, Shivamurthy PB, Prasad TS, Kanekar S, Velikkakath AK. Phosphoregulation for Therapeutic Interventions in Cancer? Phosphoregulatory Map of Checkpoint Kinase 1 (CHK1) Uncovers Unexplored Regulatory Layers. OMICS: A Journal of Integrative Biology. 2025:15578100251408291.
  30. Baby BM, Subramaniyan Y, Rekha PD. Concurrent bacterial infections in oral cancer: risk and mitigation strategies. Future Microbiology. 2025;28:1-5.
  31. Sreelakshmi K, Hemavathi KN, Raju R, Sameer KV, Keshava Prasad TS, Sudhakaran PR, Abhinand CS. Identification and stability analysis of potential ADP-ribose modification sites on vascular endothelial growth factor (VEGF) through molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics. 2025;43(7):3406-14.
  32. Naik B, Sasikumar J, Das SP. From skin and gut to the brain: the infectious journey of the human commensal fungus malassezia and its neurological consequences. Molecular Neurobiology. 2025;62(1):533-56.
  33. Krishnan S, Kanthaje S, Rekha PD, Mujeeburahiman M, Ratnacaram CK. Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer. International Review of Cell and Molecular Biology. 2025;391:135-97.
  34. Sirota SB, Doxey MC, Dominguez RM, Bender RG, Vongpradith A, Albertson SB, Novotney A, Burkart K, Carter A, Abdi P, Abdoun M. Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021. The Lancet Infectious Diseases. 2025;25(1):36-51.
  35. Kapoor A, Meitei NS, Bisht VS, Najar MA, Giri K, Prasad TS, Ambatipudi K. Lactation stage-specific variations in health and lipid-associated milk fat globule membrane proteins in Holstein Friesian cow and Murrah buffalo. International Dairy Journal. 2025;160:106114.
  36. Hemavathi KN, Middha SK, Raju R, Pilankatta R, Keshava Prasad TS, Abhinand CS. Computational screening of phytocompounds from C. amboinicus identifies potential inhibitors of influenza A (H3N2) virus by targeting hemagglutinin. Journal of Biomolecular Structure and Dynamics. 2025;43(12):6303-15.
  37. Dcunha R, Aravind A, Bhaskar S, Mutalik S, Mutalik S, Kalthur SG, Kumar A, Hegde P, Adiga SK, Zhao Y, Kannan N. Enhanced cell survival in prepubertal testicular tissue cryopreserved with membrane lipids and antioxidants rich cryopreservation medium. Cell and Tissue Research. 2025;399(1):97-117.
  38. Shanavas S, Sen U, Banerjee R, Shenoy P S, Bose B. Effective Targeting of Colorectal Cancer Stem Cells by Inducing Differentiation Mediated by Low?Dose Vitamin C via ??Catenin Retention in the Cell Membrane. Journal of Cellular Biochemistry. 2025;126(1):e30686.
  39. Shastry RP, Ghate SD, Rao RS, Giri J, Mallik S, Zhao Z. Guaiazulene and aureusidin inhibit metabolic adaptability and virulence in Candida albicans by targeting the glyoxylate cycle under alternative carbon conditions. Green Chemistry Letters and Reviews. 2025;18(1):2438073.
  40. Mallick S, Duttaroy AK, Bose B. A snapshot of cytokine dynamics: a fine balance between health and disease. Journal of Cellular Biochemistry. 2025;126(1):e30680.
  41. Shah S, Paudel MR, Thapa BB, Sharma H, Kashyap AK, Rekadwad BN, Sharma R, Sharma J, Pant B. Extract from endophytic Fusarium isolates stimulates seed germination of the host and protocorm development of non-host orchids. Communicative & Integrative Biology. 2025;18(1):2439798.
  42. Priyadarshini S, Bhat RS, Bindu AG, Nagaraj P, Rekha PD. Copper-nickel alloy coating on mild steel from electrolytic bath using co-electrodeposition for improved corrosion resistance. Results in Surfaces and Interfaces. 2025;18:100402.
  43. Yang J, Wang X, Wang K, Zeng D, Mo L, Li S, Fang B, Rekadwad B, Li W, Pu G. Mature Tiankengs are biodiversity hotspots of soil microorganisms in the karst region. Ecological Indicators. 2025;170:113034.
  44. Sasikumar J, Ebrahim RA, Das SP. Diverse Colonisation and Disease Associations of the Human Commensal Malassezia: Our Body's Secret Tenant. Mycoses. 2025;68(1):e70014.
  45. Hameed A, McDonagh F, Sengupta P, Miliotis G, Sivabalan SK, Szydlowski L, Simpson A, Singh NK, Rekha PD, Raman K, Venkateswaran K. Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus. Microbiology Spectrum. 2025;13(1):e01376-24.
  46. Kumar MP, Kini S, Prathap MS, Kudva AR, Sidheeque A, Prabhu A. In vitro cytotoxicity evaluation of endodontic irrigants combined with cationic peptide. Journal of Conservative Dentistry and Endodontics. 2025;28(1):84-9.
  47. Riha Parvin SM, Panakaje N, K M, Sheikh N, Irfana S. Development and validation of social inclusion scale for stock market participation. Cogent Economics & Finance. 2025;13(1):2453585.
  48. Fida F, Yuvarajan S, Ashwath K, Rekha PD. Lactiplantibacillus plantarum exerts anticancer effects and increase the chemosensitivity of 5-fluorouracil against oral cancer cells in vitro. BioImpacts: BI. 2024;15:30427.
  49. Bhavi SM, Thokchom B, Singh SR, Bajire SK, Shastry RP, Srinath BS, Bhat SS, Dupadahalli K, Govindasamy C, Chalekar SR, Harini BP. Syzygium malaccense leaf extract-mediated silver nanoparticles: synthesis, characterization, and biomedical evaluation in Caenorhabditis elegans and lung cancer cell line. Green Chemistry Letters and Reviews. 2025;18(1):2456624.
  50. KJ S. Ethnobotany to bioprospecting of medicinal plants from Western Ghats, India–A review. Indian Journal of Traditional Knowledge (IJTK). 2025;24(1):63-72.

Testimonials

An excellent facility with superior scope

Dr. VijayRaghavan

Secretary, DBT, New Delhi
Nice to see a bubbling group of researchers in a new upcoming research centre

Bharat Ratna Dr. C. N. R Rao

Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Proud to see such wonderful work at the facility and in faraway Mangalore

Dr. A. K. D’Cruz

Director-Tata Memorial Hospital, Mumbai
I was excited to see the advancement done by the institution in every aspect of medical science including latest laboratory in the premise. I pray the God that this institution will prosper and give benefit to the nation in health sector

Shri Shripad Yesso Naik

The Union Minister of AYUSH, Government of India
Wonderful facility! Research is the future to solve issues in medicine. I am very impressed with the passion of the faculty in R & D. Keep up the good work

Faizal E. Kottikollon and Shabana Faizal

Faizal Shabana Foundation, Bangalore
It is very good to see how committed you are with research

Dr. Claudio Almeida Quadros

Bahia State University, Brazil
An ideal facility positioning with cutting edge research and talented researchers right in the middle of a hospital, just what is needed for the translational research

Prof. Pauline Ford

School of Dentistry, The University of Queensland, Australia

Certifications