Somi Shrivastava
JRF
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MSc (Area): Biotechnology
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somishri@gmail.com
Ms. Somi Shrivastava completed her Master’s degree in Biotechnology from Dr. Hari Singh Gour (Central) University, 2017, Sagar, India. During her masters she worked on a project entitled “Ameliorative effect of Resveratrol on Aflatoxin B1 induced renal toxicity”. Currently she is working on Cancer biology, stem cells and regenerative medicine.
Experience
- Junior Research Fellow (April 2019 – till date) – Stem Cells and Regenerative Medicine Centre (SCRMC), Yenepoya Research Centre, Yenepoya (Deemed to be University)
Awards/Honors
- DBT-Bitp (Biotech Industrial Training Program) 2018
- CSIR-UGC NET LECTURSHIP (AIR 41) 2017
- Completed GIAN (Global Initiative of Academic Networks) program on “Chemometrics and Liquid Chromatographic Method Development” at Department of Criminology and Forensic Science, Dr. Hari Singh Gour University, Sagar, India and obtained A+ grade in it.
- GIAN programme on “Molecular Virology: Biotechnology tools for controlling viral diseases” at Department of Biotechnology, Dr. Hari Singh Gour University, Sagar, November, 2016
- Best poster award at “National conference on Emerging Trends in Biological Sciences.” held at Bhopal, February, 2015
Research Interest/Area
Cancer Biology, Molecular Biology, Cell Biology, Stem Cell and Regenerative biology
Research
Cancer is the primary cause of public health problem globally. Chemical carcinogenesis is a multicausal and multistage process, in which the healthy cells first initiated, then become malignant and invasive. Each stage is characterized by biochemical, morphological phenotype and genetic changes, which results in mutations, and epigenetic alterations. Generally, the observation of the morphological, genetic, and biochemical changes consider the adaptation of healthy cells to neoplastic cells to survive in a familiar but antagonistic environment. Inside the tumor microenvironment, CSCs exhibit numerous characters such as proliferation, multi-lineage differentiation, and auto regeneration. Tumor exists in a specific cellular environment i.e., the tumor microenvironment (TME). TME comprise of stromal cells, hypoxic regions, proliferating tumor cells, networks of cytokines, extracellular matrix, fibroblasts, and immune cells. Recently we are focusing on the role of food adulterants, as carcinogenic inducer, and its role towards developing carcinogenesis on normal cells in the murine and human model.
Publications
- D Rawat, S Shrivastava, RA Naik, SK Chonker, A Mehrotra, RK Koiri (2018) An overview of natural plant products in the treatment of hepatocellular carcinoma. Anticancer Agents in Medicinal Chemistry.doi: 10. 2174/1871520618666180604085612